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KMID : 0360220130540030462
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Journal of the Korean Ophthalmological Society
2013 Volume.54 No. 3 p.462 ~ p.468
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Optic Cup Slope as a Numeric Representative of Glaucomatous Cupping
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Ahn Sang-Il
Chang Jee-Ho
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Abstract
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Purpose: To objectively define the degree of cupping, the authors extracted 3-dimensional slope surface maps from Cirrus HDTM-OCT data and assessed their differentiating characteristics between normal subjects and glaucomatous patients. Methods: One eye from each of 40 normal subjects and 1 eye from each of 39 patients with glaucoma were examined using automated visual field perimetry and Cirrus HDTM-OCT. The Optic Disc Cube 200 × 200 protocol was performed. The individual OCT data were reconstructed as the 3-dimensional surface maps of the optic disc cup and the slope of each contour was calculated using custom-developed software. Several disc cup slope parameters were derived. The parameters measuring the internal features of the optic disc cup were calculated and compared between groups. Results: Sum of cup slope, sum of thresholded cup slope, and sum of thresholded cup slope / thresholded cup area parameters were differentiating factors between the normal and glaucoma groups (p < 0.05). The area under the receiver operating characteristic curve (AUROC) value of the slope parameters ranged from 0.718 to 0.753. The sum of thresholded cup slope / thresholded cup area parameter was well correlated with visual field mean deviation (r = -0.250, p = 0.028). Conclusions: The optic disc cup slope parameter obtained with OCT may be a useful parameter for representing glaucomatous cupping.
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KEYWORD
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Cup slope, Disc cup, Glaucoma, OCT
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